Melanoma is the deadliest skin cancer with increasing incidence rates worldwide. Trying to find new therapeutic opportunities for this disease is at the forefront of cancer research. In this context, Prof. Yardena Samuels uses whole exome and whole genome sequencing approaches to identify and characterize novel tumor-specific mutations that may contribute to the disease. Their 120 low-passage melanoma cell lines put Samuels’ lab in a unique position to decipher the functional effects of discovered mutations in their physiological context.
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